New compound could rid stem cell samples of potentially tumorigenic cells
Stem cells derived from adult cells, called human induced pluripotent stem cells (hiPSCs), have great potential for basic research and regeneration therapies. But for clinical samples to be safe, these...
View ArticlePalldium(II) dithiocarbamates—anticancer metallodrugs of the future?
Most chemistry students are well aware of the anticancer properties of cisplatin, cis-Pt(NH3)2Cl2, as a result of the pioneering work of Professor Barnett Rosenberg and his colleagues at the Michigan...
View ArticleUsing 'chemical origami' to generate customisable, high-value chemicals from...
Following the discovery of a new and very valuable enzyme which folds linear molecules into different shapes, scientists at the John Innes Centre are building a 'triterpene machine' which will enable...
View ArticleDrug delivery that hits the dot
Drug treatments are made more efficient by delivering them to specific sites in the body where they are needed. For example, specific targeting of anticancer drugs to tumour sites could reduce required...
View ArticleScientists synthesize new molecules with anticancer and antioxidant activity
A group of scientists from Moscow universities led by Yan Ivanenkov, the head of Laboratory of Medical Chemistry and Bioinformatics in MIPT, has succeeded in synthesizing a set of novel...
View ArticleTeam screens cardiac drugs that also attack cancer
Several drugs now being used to treat heart failure and atrial arrhythmia also show promise as DNA disruptors in cancer cells and could be readily repurposed as anticancer agents, according to a new...
View Article3-D structure of enzyme critical to creation of anticancer compounds in...
Scientists identify 3D structure of enzyme critical to the creation of anticancer and antimalarial compounds in plants
View ArticleResearchers disguise drugs as platelets to target cancer
Researchers have for the first time developed a technique that coats anticancer drugs in membranes made from a patient's own platelets, allowing the drugs to last longer in the body and attack both...
View ArticleGreen tea as a therapeutic delivery system for anticancer drugs
The humble cup of tea has long been regarded as a cure-all for the hustle and bustle of modern life. Now, researchers from the A*STAR Institute of Bioengineering and Nanotechnology have identified...
View ArticleNew target for anticancer drugs—RNA
Most of today's anticancer drugs target the DNA or proteins in tumor cells, but a new discovery by University of California, Berkeley, scientists unveils a whole new set of potential targets: the RNA...
View ArticleNano-hydrogels that attack cancer cells
Hydrogels are materials that are commonly used in everyday objects such as contact lenses or diapers, in order to control humidity. However, chemical engineers at the University of Guadalajara (UdeG),...
View ArticleBeer compound could help fend off Alzheimer's and Parkinson's diseases
The health-promoting perks of wine have attracted the spotlight recently, leaving beer in the shadows. But scientists are discovering new ways in which the latter could be a more healthful beverage...
View ArticleDrugs from dirt: Scientists develop first global roadmap for drug discovery
Rockefeller University scientists have analysed soils from beaches, forests, and deserts on five continents and discovered the best places in the world to mine untapped antibiotic and anticancer drugs....
View ArticleCancer-killing nanodaisies
NC State researchers have developed a potential new weapon in the fight against cancer: a daisy-shaped drug carrier that's many thousands of times smaller than the period at the end of this sentence.
View ArticleResearcher uses Jell-O-like substance to attract and kill cancer cells
(Phys.org) —Chasing cancer cells with chemotherapy drugs can save lives, but there's no guarantee that the treatment will kill every run-away cancer cell in the body.
View ArticleDiscovery of how Taxol works could lead to better anticancer drugs
University of California, Berkeley, scientists have discovered the extremely subtle effect that the prescription drug Taxol has inside cells that makes it one of the most widely used anticancer agents...
View ArticleRare byproduct of marine bacteria kills cancer cells by snipping their DNA
(Phys.org) —Yale University researchers have determined how a scarce molecule produced by marine bacteria can kill cancer cells, paving the way for the development of new, low-dose chemotherapies.
View ArticleCancer drugs hitch a ride on 'smart' gold nanoshells
Nanoparticles capable of delivering drugs to specifically targeted cancer cells have been created by a group of researchers from China.
View ArticleNew insights into network that plays crucial role in cell function and disease
A new research paper from the labs of University of Notre Dame researchers Holly Goodson and Mark Alber helps resolve an ongoing debate about the assembly of a subcellular network that plays a critical...
View ArticleCurve ball: New approaches, surprising results challenge fundamental...
(Phys.org) —After analyzing hundreds of interactions between cancer drugs and cancer cells using information theory and advanced modeling techniques, Harvard Medical School researchers have found that...
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