Self-assembling nanofilaments enhance drug delivery
(Phys.org)—While most nanoparticles under development as drug delivery vehicles are spheres, a growing body of research suggests that cylindrical nanoparticles would perform even better at the twin...
View ArticleStructure of enzyme unravelled providing basis for more accurate design of...
A group of researchers at the University of California, Berkeley have for the first time described the structure of the active site core of topoisomerase II alpha, an important target for anti-cancer...
View ArticleIt takes two to tangle: Scientists further unravel telomere biology
Chromosomes - long, linear DNA molecules – are capped at their ends with special DNA structures called telomeres and an assortment of proteins, which together act as a protective sheath. Telomeres are...
View ArticleDevelopment of the first way to make large amounts of promising anti-cancer...
Scientists are reporting development of the first practical way to make large amounts of a promising new anti-cancer substance that kills cancer cells differently than existing medicines. Their article...
View ArticleNew tool for mining bacterial genome for novel drugs
Vanderbilt biochemists have discovered that the process bacteria undergo when they become drug resistant can act as a powerful tool for drug discovery.
View ArticlePhoto-immunotherapy boosts nanoparticle delivery to tumors
(Phys.org)—One of the main reasons that nanoparticles can boost the effectiveness of an anticancer drug while decreasing its toxicity is that they are able to accumulate at cancerous sites in the body...
View ArticleStudy of several dozen compounds based on a fungal chemical shows potent...
Inspired by a chemical that fungi secrete to defend their territory, MIT chemists have synthesized and tested several dozen compounds that may hold promise as potential cancer drugs.
View ArticleA new family of aniontransporters to fight against cancer
The journal Accounts of Chemical Research has published the article "Anion Transporters and Biological Systems", by Professor Ricardo Pérez Tomás, from the Department of Pathology and Experimental...
View ArticleNano-needles can force medicine into cells, even when they resist taking it
Physicist Pawel Sikorski and his group are making beds of nails on a miniature scale – a plate covered in nano-needles designed to puncture individual cells.
View ArticleComplex responsible for protein breakdown in cells identified using Bio TEM
Using TEM to observe protein molecules and analysing its high resolution 3D structure is now possible. KAIST Biomedical Science and Engineering Department's Professor Ho-Min Kim has identified the high...
View ArticleSuccess in inducing natural death of epithelial cancer cells by...
A research team from the National Institute for Materials Science has developed a new nanofiber mesh which is capable of simultaneously realizing thermotherapy (hyperthermia) and chemotherapy...
View ArticleNanoparticles, 'pH phoresis' could improve cancer drug delivery
(Phys.org) —Researchers have developed a concept to potentially improve delivery of drugs for cancer treatment using nanoparticles that concentrate and expand in the presence of higher acidity found in...
View ArticleOne nanoparticle plus one antibody equals targeted drug delivery to tumors
(Phys.org) —Herceptin and camptothecin are both powerful anticancer agents with key characteristics that limit their effectiveness in treating cancer. Patients treated with Herceptin, a monoclonal...
View ArticleSmart anticancer nanofibers: Setting treatments to work together
Japanese researchers report that incorporating magnetic nanoparticles and an anticancer drug into crosslinked polymer nanofibers presents a twofold treatment for fighting cancer with diminished side...
View ArticleEucalyptus macrocarpa is giving nano-medicine a boost
(Phys.org) —Murdoch University researchers have developed a 'green' method to create antibacterial gold nanoparticles for potential use in the medical field with the help of common eucalyptus leaves.
View ArticleChemists design 'smart' nanoparticles to improve drug delivery, DNA...
A team of chemists in SU's College of Arts and Scientists has used a temperature-sensitive polymer to regulate DNA interactions in both a DNA-mediated assembly system and a DNA-encoded drug-delivery...
View ArticleCurve ball: New approaches, surprising results challenge fundamental...
(Phys.org) —After analyzing hundreds of interactions between cancer drugs and cancer cells using information theory and advanced modeling techniques, Harvard Medical School researchers have found that...
View ArticleNew insights into network that plays crucial role in cell function and disease
A new research paper from the labs of University of Notre Dame researchers Holly Goodson and Mark Alber helps resolve an ongoing debate about the assembly of a subcellular network that plays a critical...
View ArticleCancer drugs hitch a ride on 'smart' gold nanoshells
Nanoparticles capable of delivering drugs to specifically targeted cancer cells have been created by a group of researchers from China.
View ArticleRare byproduct of marine bacteria kills cancer cells by snipping their DNA
(Phys.org) —Yale University researchers have determined how a scarce molecule produced by marine bacteria can kill cancer cells, paving the way for the development of new, low-dose chemotherapies.
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